Abstract

We wanted to investigate nephrogenesis in its ontogenetic development (in the perinatal periods). This perinatal time interval was divided into five periods. Intrauterine are the early fetal (3–5 months) and late fetal periods, neonates (0–1 months), infants (1–12 months) and young children (1–3 years). We only conducted the analysis until the age of three, because the one million nephron number characteristic of the kidney in adulthood is already developed by the age of three. We found that the structural and functional unit of the kidney is the nephron, which undergoes three initial stages: pro-, meso- and metanephros. There are two periods of accumulation: late fetal and infant age. After birth, the number of incomplete renal corpuscles is negligible. In further periods of ontogenesis, the nephron count remains unchanged, only the volume of the nephrons increases. When modeling kidney function, we found that the body is “resting” some of the nephrons, because it is during this time that the cell walls resulting from cavitation are regenerated

Keywords: nephrogenesis, biophysical modelling, perinatal periods, ontogenetic development of the kidneys

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How to Cite
[1]
Vincze, J. and Tiszay, G.V. 2020. The Nephrogenesis in the Human Organism. International Journal of Science and Engineering Invention. 6, 11 (Jun. 2020), 1 to 4. DOI:https://doi.org/10.23958/ijsei/vol06-i03/199.

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Copyright © 2020 Janos Vincze Gabriella Vincze Tiszay this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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This work is licensed under a Creative Commons Attribution 4.0 International License.